No. It seems to be in the $BCaseList object in R5. (R4 and Notes 6 use different data structures.) 22 bytes before the file name, a byte contains 1 for send, 2 for receive, and 4 for some unknown purpose. So the usual value is 7. You can get at this data by using API calls, although I attacked names.nsf manually with a hex editor because it was quicker than writing code. If you wanted to change the value, you might run into problems if it is cached in memory by the client. I have not tried it.
The replication options are meant to be a user preference, and it is probably not a good idea to use code to fiddle with them even if it turns out to be possible. Generally, to stop people making modifications to a database you give them Reader access. To allow people to submit documents but not read documents, you can use Depositor access. If you really want to force people to use the server for certain tasks, you can code this in form events.
Many of the database settings in the icon note are documented in the C API package, in the file STDNAMES.H. I think someone posted an extract in the forum once. You can get the latest C API versions from the Sandbox.