Notes/Domino 4 and 5 Forum

Is posible to search for multiples substrings and replacing them by a set of characters in one line of code? May be a combination of Instr and Mid function?
Example:

I want to find the "," and ":" in the string "Hi, my name is: John" and replace the "," for "COMA" and ":" for "DOSP". The result would be line this:

"HiCOMA my name isDOSP John"

Can anybody tell me if it is posible?
Thanks,

Juan M. Bellina
jbellina@fys.com.ar