I got it all working but I doubt you can set it up on 2-3 machines due to port, host name and virtual server conflicts.
I've set it up as recommended on 8 servers. The only components I combined were ST Proxy Registrar and ST Conference Manager (which makes clustering impossible at a later point). Note that the installation guide points out 16 CPUs and 16 GB RAM each are recommended for the two other video components... If the MCU has less then 16 CPUs it complains about insufficient resources.
"The Video Manager and the Video MCU each must be on its own computer. Best practice calls for 16 core, 16 GB for each computer."